Call us: Mon-Sat 8:30AM-6PM, Sun 9AM-2PM 0800 031 8386
Call us: Mon-Sat 8:30AM-6PM, Sun 9AM-2PM 0800 031 8386
Boots Advantage Card Shop
Royal Mail Strikes - Click here to see the latest updates
Advantage card
Collect points for every £1 spent


Advantage card
Collect points for every £1 spent


What is it and does it work for weight loss?

Weight Loss Treatment

What is Rybelsus?

Rybelsus is a medicine that comes in tablet form developed by the pharmaceutical company Novo Nordisk Inc. to treat type 2 diabetes.

It contains the active ingredient semaglutide, a synthetic version of the hormone glucagon-like peptide 1 (GLP-1).

This hormone regulates blood sugar levels by increasing insulin production and reducing glucose production by the liver.

Is Rybelsus a weight loss pill?

Rybelsus is not licensed for use as a weight loss medicine, but its active ingredient semaglutide has been shown to help control appetite by reducing cravings and keeping people feeling fuller for longer.

Medicines containing semaglutide, in combination with healthy eating habits and regular exercise, can help weight loss.

Are Rybelsus and Ozempic the same?

Both Rybelsus and Ozempic are manufactured by Novo Nordisk Inc. They both contain the active ingredient semaglutide and are mainly used to treat type 2 diabetes. Rybelsus comes in tablet form; Ozempic is a self-injection medicine.

I’m not diabetic: can I still take Rybelsus?

Rybelsus is only licensed for the treatment of type 2 diabetes, but is sometimes prescribed off-label as a weight loss medicine. What does ‘off-label’ mean?

Where can I buy Rybelsus?

Rybelsus is a prescription-only medicine available through GPs, hospital specialists, or licensed online pharmacies.

We don’t currently prescribe Rybelsus, but we can offer other weight loss treatments where suitable.

These include Saxenda, a similar medicine also manufactured by Novo Nordisk Inc.

Saxenda contains the active ingredient liraglutide, which works in the same way as semaglutide in Rybelsus. It can help reduce hunger and cravings, leading to improved control over eating habits. Find out more about Saxenda and how it works for weight loss.

Rybelsus vs Wegovy

Rybelsus and Wegovy are both made by the same manufacturer, Novo Nordisk Inc., and contain the same active ingredient, semaglutide.

However, Wegovy has been specifically designed and licensed for use as a weight loss medicine. It’s administered via a weekly self-injection.

Wegovy isn’t currently available in the UK, but should be later this year. Find out more about Wegovy and sign up to find out when it arrives at Boots Online Doctor.

Alternative weight loss treatments

We offer a variety of weight loss treatments, including Saxenda, Orlistat, and Xenical. Saxenda, like Rybelsus, helps reduce appetite and keeps users feeling full for longer. It comes in the form of a self-injection pen.

Orlistat and Xenical are capsules that block the body's absorption of fat. For best results, these medicines should be used alongside a low-fat healthy eating plan.

Need treatment?

Weight Loss Treatment
Clinical review within 2–24 hrs  
Repeat prescriptions available

Need help losing weight?

Healthy, sustainable weight loss is down to more than just taking medicine. At Boots Online Doctor we have a wide range of helpful resources available to assist you with weight loss.

Check out our recommended eating plans, live webinars with our expert lifestyle medicine team where you can get all your weight loss questions answered, and our new ten-week weight loss programme.

These are all available completely free to anyone who wants extra support losing weight.

What are the side effects of Rybelsus?

Like all medicine, Rybelsus can cause some side effects. The most common side effects of Rybelsus include nausea, diarrhoea and vomiting.

These side effects usually subside after a few weeks of treatment. Rare but serious side effects may also occur, such as pancreatitis, kidney problems, and low blood sugar.

Start your weight loss journey
Approved By:

Last reviewed on: 14/09/2023